Evolution during primary HIV infection does not require adaptive immune selection [Biophysics and Computational Biology]

Modern HIV research depends crucially on both viral sequencing and population measurements. To directly link mechanistic biological processes and evolutionary dynamics during HIV infection, we developed multiple within-host phylodynamic models of HIV primary infection for comparative validation against viral load and evolutionary dynamics data. The optimal model of primary infection...

Source: Proceedings of the National Academy of Sciences - February 10, 2022 Category: Science Authors: David A. Swan, Morgane Rolland, Joshua T. Herbeck, Joshua T. Schiffer, Daniel B. Reeves Tags: Evolution Biological Sciences Source Type: research