SUVmax to tumor perimeter distance: a robust radiomics prognostic biomarker in resectable non-small cell lung cancer patients

ConclusionThe geometric variables, nSCD and nSPD, are robust biomarkers of the poorest outcome prediction of patients with NSCLC with respect to classical PET variables.Key Points•In NSCLC patients, it is crucial to find prognostic parameters since  TNM system alone cannot explain the variation in lung cancer survival.•Age, lymphovascular invasion, lymph nodal infiltration, and metabolic geometrical parameters were useful as prognostic parameters.•The displacement grade of the highest point of metabolic activity towards the periphery assessed by geometric variables obtained from [18F]FDG  PET/CT was a robust biomarker of the poorest outcome prediction of patients with NSCLC.
Source: European Radiology - Category: Radiology Source Type: research