Proteomic evaluation of Alternaria alternata spores, hyphae, and commercial allergen extracts

Alternaria alternata is associated with allergic respiratory diseases, which can be managed with allergen extract-based diagnostics and immunotherapy. It is not known how asexual spores or the vegetative hyphae contribute to patient allergen reactivity and commercial allergen extracts are manufactured by extracting proteins without separating these components. Immunotherapy and diagnosis with existing products, while safe and effective, could be improved with better characterization of these elements.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research