68Ga-PSMA-11 uptake in tracheal mucus plug – a potential pitfall

We report a case of PCa in which68 Ga-PSMA-11 uptake was noted in the tracheal lumen. However,18F-PSMA-1007 PET/CT was done on a subsequent day, which demonstrated no abnormal radiotracer uptake or morphological lesion within the tracheal lumen. This case highlights an uncommon finding of PSMA ligand uptake in a tracheal mucus plug (non-prostatic benign uptake), which may be misinterpreted as a false-positive finding.
Source: Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research