The role of immunohistochemistry in diagnostic breast pathology

Using an entity and differential diagnosis based approach, this paper reviews the role of immunohistochemistry as an adjunct to morphology in the diagnosis and categorization of (1) intraductal epithelial cell proliferations (2) lobular neoplasia (3) glandular proliferations, papillary lesions and subtle invasive breast carcinoma (4) spindle cell lesions and (5) metastases to and from the breast. Brief descriptions of the pathological features are included with emphasis on useful antibodies and their limitations.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: Breast pathology Source Type: research