Response to Comment on Meek et al. Reappearance of C-Peptide During the Third Trimester in Type 1 Diabetes Pregnancy: Pancreatic Regeneration or Fetal Hyperinsulinism? Diabetes Care 2021;44:1826 –1834

We read with interest the letter and study synopsis from Ivanisevic and Djelmis (1) and published descriptions (n = ∼30) of their cohort of pregnant women with type 1 diabetes (T1D) (2). It is unclear how many of their participants had detectable C-peptide at baseline. Typically,<50% of women with T1D have detectable C-peptide in early pregnancy, suggesting residual β-cell function (3).
Source: Diabetes Care - Category: Endocrinology Source Type: research