The combination of TRAIL and the Smac mimetic LCL-161 induces an irreversible phenotypic change of MCF-7 breast cancer cells

CONCLUSIONS: The results demonstrate that LCL-161 and TRAIL can irreversibly alter the MCF-7 breast cancer cell phenotype. However, the changes in morphology and global gene expression are mediated via separate pathways.PMID:35007560 | DOI:10.1016/j.yexmp.2021.104739
Source: Experimental and Molecular Pathology - Category: Pathology Authors: Source Type: research