Daldinans D ‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica

AbstractFour new isoindolinone derivatives, daldinans D ‒G (3‒6), together with two known compounds, daldinans A and B (1 and2), were isolated from the stroma of the ascomyceteDaldinia concentrica. Chemical structures of the isolated compounds were determined by spectroscopic methods. All of these compounds exhibited antioxidant activities with IC50 values of 3.21 to 39.67  µM in the 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research