What Factors Are Associated with Local Metastatic Lesion Progression After Intramedullary Nail Stabilization?

CONCLUSION: Our analysis suggests that for this population of patients with metastatic bone disease who have a fracture or impeding fracture and an anticipated survival of at least 6 weeks (completed fracture) or 3 months (impending fracture), the risk of experiencing local progression of tumor growth and reoperations after intramedullary nail stabilization seems to be low. Lesion progression was not associated with the duration of survival, although this conclusion is limited by the small number of patients in the current study and the competing risks of survival and local progression. Based on our data, patients who present with renal cell carcinoma should be cautioned against undergoing intramedullary nailing because of the risk of postoperative lesion progression.LEVEL OF EVIDENCE: Level III, therapeutic study.PMID:34962492 | DOI:10.1097/CORR.0000000000002104
Source: Clinical Orthopaedics and Related Research - Category: Orthopaedics Authors: Source Type: research