Clinical Impact of Pitolisant on Excessive Daytime Sleepiness and Cataplexy in Adults With Narcolepsy: An Analysis of Randomized Placebo-Controlled Trials

ConclusionsThe results of this analysis demonstrate the robust efficacy of pitolisant for the reduction in both excessive daytime sleepiness and cataplexy. These large effect sizes and low NNTs provide further evidence supporting the strength of the clinical response to pitolisant in the treatment of adults with narcolepsy.Clinical Trial RegistrationClinicalTrials.gov identifiers: NCT01067222 (February 2010), NCT01800045 (February 2013).
Source: CNS Drugs - Category: Neurology Source Type: research