Multicomponent material property characterization of atherosclerotic human carotid arteries through a Bayesian Optimization based inverse finite element approach

CONCLUSION: The developed iFEM approach combined with the inverted GP model successfully predicted component-wise material properties of intact atherosclerotic human carotids ex-vivo under physiological-like loading conditions.SIGNIFICANCE: We developed a novel iFEM framework for the nonlinear, component-wise material characterization of atherosclerotic arteries and utilized it to obtain human atherosclerotic carotid material properties. The developed iFEM framework has great potential to be advanced for patient-specific in-vivo application.PMID:34864574 | DOI:10.1016/j.jmbbm.2021.104996

Source: Journal of the Mechanical Behavior of Biomedical Materials - December 5, 2021 Category: Materials Science Authors: Su Guvenir Torun Hakki M Torun Hendrik H G Hansen Chris L de Korte Antonius F W van der Steen Frank J H Gijsen Ali C Akyildiz Source Type: research