Family history of breast cancer is associated with elevated risk of prostate cancer: evidence for shared genetic risks

Conclusion: This st udy shows the inherent relation between prostate cancer and breast cancer; an incident of one in a family increases the risk of developing the other. The large difference between estimates of genetic correlation from distant and close relatives, if replicated, suggests that rare variants contribute to the shared genetic risk of breast and prostate cancer. However, the difference could steam from genotype-by-family effects shared between the two types of cancers.
Source: Human Heredity - Category: Genetics & Stem Cells Source Type: research