Cancers, Vol. 13, Pages 6021: EBV-Driven Lymphoproliferative Disorders and Lymphomas of the Gastrointestinal Tract: A Spectrum of Entities with a Common Denominator (Part 3)
Cancers, Vol. 13, Pages 6021: EBV-Driven Lymphoproliferative Disorders and Lymphomas of the Gastrointestinal Tract: A Spectrum of Entities with a Common Denominator (Part 3)
Cancers doi: 10.3390/cancers13236021
Authors:
Magda Zanelli
Francesca Sanguedolce
Andrea Palicelli
Maurizio Zizzo
Giovanni Martino
Cecilia Caprera
Valentina Fragliasso
Alessandra Soriano
Fabrizio Gozzi
Luca Cimino
Francesco Masia
Marina Moretti
Moira Foroni
Loredana De Marco
David Pellegrini
Hendrik De Raeve
Stefano Ricci
Ione Tamagnini
Alessandro Tafuni
Alberto Cavazza
Francesco Merli
Stefano A. Pileri
Stefano Ascani
EBV is the first known oncogenic virus involved in the development of several tumors. The majority of the global population are infected with the virus early in life and the virus persists throughout life, in a latent stage, and usually within B lymphocytes. Despite the worldwide diffusion of EBV infection, EBV-associated diseases develop in only in a small subset of individuals often when conditions of immunosuppression disrupt the balance between the infection and host immune system. EBV-driven lymphoid proliferations are either of B-cell or T/NK-cell origin, and range from disorders with an indolent behavior to aggressive lymphomas. In this review, which is divided in three parts, we provide an update of EBV-associated lymphoid disorders developing in the gastrointestinal tract, often representing a challenging diagnostic and therapeutic...
Source: Cancers - Category: Cancer & Oncology Authors: Magda Zanelli Francesca Sanguedolce Andrea Palicelli Maurizio Zizzo Giovanni Martino Cecilia Caprera Valentina Fragliasso Alessandra Soriano Fabrizio Gozzi Luca Cimino Francesco Masia Marina Moretti Moira Foroni Loredana De Marco David Pellegrini Hendrik Tags: Review Source Type: research
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