Delphinidin diminishes in vitro interferon- γ and interleukin-17 producing cells in patients with psoriatic disease

In conclusion, delphinidin exerts a profound in vitro anti-inflammatory effect in psoriasis and psoriatic arthritis by inhibiting IFNγ+ innate and adaptive cells and T helper (Th) 17 cells. If this effect is also exerted in vivo, delphinidin may be regarded as a nutraceutical with immunosuppressive potential.PMID:34825313 | DOI:10.1007/s12026-021-09251-y

Source: Cell Research - November 26, 2021 Category: Cytology Authors: Sotirios G Tsiogkas Αthanasios Mavropoulos Dimitrios N Skyvalidas Eleni Patrikiou Niki Ntavari Athina Ioanna Daponte Maria G Grammatikopoulou Efthimios Dardiotis Aggeliki-Victoria Roussaki-Schulze Lazaros I Sakkas Efterpi Zafiriou Dimitrios P Bogdanos Source Type: research