MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3

Conclusions:
Our study demonstrates for the first time that platelet-secreted miR-223 via P-MVs can promote lung cancer cell invasion via targeting tumor suppressor EPB41L3.

Source: Molecular Cancer - March 11, 2015 Category: Cancer & Oncology Authors: Hongwei LiangXin YanYi PanYongsheng WangNan WangLimin LiYuan LiuXi ChenChen-Yu ZhangHongwei GuKe Zen Source Type: research