CCL19 associates with lymph node metastasis and inferior prognosis in patients with small cell lung cancer

Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer [1] . Majority of them were initially diagnosed as extensive stage small cell lung cancer (ES-SCLC)[2 –4]. Although chemotherapy plus immunotherapy has been the standard of care in front setting, the prognosis in patients with extensive SCLC is still dismal with a median OS of around 12 months[5]. Therefore, a deeper understanding of SCLC pathogenesis to develop potential novel approaches are urge ntly needed.

Source: Lung Cancer - November 10, 2021 Category: Cancer & Oncology Authors: Qian Liu, Meng Qiao, Zoltan Lohinai, Shiqi Mao, Yingying Pan, Yan Wang, Shuo Yang, Fei Zhou, Tao Jiang, Xianghua Yi, Shengxiang Ren, Caicun Zhou, Fred R. Hirsch Source Type: research