Downregulation of miR-223 promotes HMGB2 expression and induces oxidative stress to activate JNK and promote autophagy in an in vitro model of acute lung injury

Excessive autophagic activity in alveolar epithelial cells is one of the main causes of acute lung injury (ALI), but the underlying molecular mechanism has not been fully elucidated. Previous studies have show...

Source: Journal of Inflammation - November 3, 2021 Category: Allergy & Immunology Authors: Hao-Yu Tan, Bei Qing, Xian-Mei Luo and Heng-Xing Liang Tags: Research Source Type: research