Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships

Zhang et al. (Proc Natl Acad Sci 118:e2105968118, 2021) recently reported that SARS-CoV-2 RNA can be retrotranscribed and integrated into the DNA of human cells by the L1 retrotransposon machinery. This phenom...

Source: Retrovirology - October 29, 2021 Category: Virology Authors: Nicole Grandi, Enzo Tramontano and Ben Berkhout Tags: Commentary Source Type: research