Viruses, Vol. 13, Pages 2144: Ongoing Assessment of the Molecular Evolution of Peste Des Petits Ruminants Virus Continues to Question Viral Origins

Viruses, Vol. 13, Pages 2144: Ongoing Assessment of the Molecular Evolution of Peste Des Petits Ruminants Virus Continues to Question Viral Origins Viruses doi: 10.3390/v13112144 Authors: Mana Mahapatra Richa Pachauri Saravanan Subramaniam Ashley C. Banyard Shanmugam ChandraSekar Muthannan Andavar Ramakrishnan Felix Njeumi Dhanavelu Muthuchelvan Satya Parida Understanding the evolution of viral pathogens is critical to being able to define how viruses emerge within different landscapes. Host susceptibility, which is spread between different species and is a contributing factor to the subsequent epidemiology of a disease, is defined by virus detection and subsequent characterization. Peste des petits ruminants virus is a plague of small ruminant species that is a considerable burden to the development of sustainable agriculture across Africa and much of Asia. The virus has also had a significant impact on populations of endangered species in recent years, highlighting its significance as a pathogen of high concern across different regions of the globe. Here, we have re-evaluated the molecular evolution of this virus using novel genetic data to try and further resolve the molecular epidemiology of this disease. Viral isolates are genetically characterized into four lineages (I−IV), and the historic origin of these lineages is of considerable interest to the molecular evolution of the virus. Our re-evaluation of viral emergence using novel genome sequen...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research