In Utero Gene Therapy for Primary Immunodeficiencies

Primary immunodeficiencies (PIDs) have become a prime target for gene therapy given the morbidity, mortality, and the single gene etiology. Given that outcomes are better the earlier gene therapy is implemented, it is possible that fetal gene therapy may be an important future direction for the treatment of PIDs. In this chapter, the current treatments available for several PIDs will be reviewed, as well as the history and current status of gene therapy for PIDs. The possibility of in utero gene therapy as a possibility will then be discussed.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Gene Therapy in Obstetrics Source Type: research