Pediatrician Recommendations for Behavioral Treatment for Preschoolers With ADHD

This cohort study investigates the rate of pediatrician recommendations for behavioral treatment for preschoolers with an attention-deficit/hyperactivity disorder diagnosis or symptoms.
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research

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Conclusions: Individuals with increased ADHD symptoms appear to recruit the right dorsolateral prefrontal cortex more strongly to perform the same task than those with fewer symptoms. In clinical settings, individuals with severe symptoms are often observed to perform more difficultly when performing the tasks which individuals with mild symptoms can perform easily. The atomoxetine-responder group was unable to properly activate the right dorsolateral prefrontal cortex when necessary, and the oral administration of atomoxetine enabled these patients to activate this region. In brain imaging studies of heterogeneous syndrom...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
ConclusionsIn children aged 4 –5 years with ADHD, following multiple once-daily administrations of SHP465 MAS 6.25 mg, the pharmacokinetic profile of plasmad-amphetamine andl-amphetamine was generally consistent among participants. Between-individual variability of plasmad-amphetamine andl-amphetamine steady-state exposure was low to moderate. SHP465 MAS was generally well tolerated in this study.Trial RegistrationClinicalTrials.gov, NCT03327402 (31 October, 2017).
Source: CNS Drugs - Category: Neurology Source Type: research
Nervenarzt. 2021 Nov 24. doi: 10.1007/s00115-021-01233-7. Online ahead of print.ABSTRACTThe notion that the adult form of attention deficit hyperactivity disorder (ADHD) is not a construct of modern psychiatry is increasingly prevailing. Looking into the history of psychiatry can make an enlightening contribution here. Guided by this aim and specifically following literature referred to by Emil Kraepelin (1856-1926), we analyzed the content of one study each by Gustav Specht (1860-1940) and the later Nazi psychiatrist Hermann Paul Nitsche (1876-1948) from 1905 and 1910, respectively, on the topic of chronic mania. Our inve...
Source: Der Nervenarzt - Category: Neurology Authors: Source Type: research
CNS Neurol Disord Drug Targets. 2021 Nov 23. doi: 10.2174/1871527320666211124093345. Online ahead of print.ABSTRACTBACKGROUND: Attention Deficit Hyperactivity Disorder is a common child neurobehavioral disorder whose pathogenesis is not completely understood. However, some evidence indicates a crucial link between this disorder and the degree of oxidative stress. Coenzyme Q10 (ubiquinol) is an antioxidant that may play a significant role in the treatment of Attention Deficit Hyperactivity Disorder.OBJECTIVE: To assess the safety and efficacy of coenzyme Q10 as an add-on drug treatment for attention deficit hyperactivity di...
Source: CNS and Neurological Disorders Drug Targets - Category: Drugs & Pharmacology Authors: Source Type: research
Aggression is well-known problem in adolescent with Attention-Deficit/Hyperactivity Disorder (ADHD), but the precise relation of reactive and proactive aggression by gender and comorbidities has not been characterized in this population. The aim of this st...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Conclusions: Brain perfusion SPECT distinguishes adult ADHD patients without comorbidities from healthy controls. Areas which were highly significantly different from control and thus may serve as biomarkers in baseline SPECT scans included: medial anterior prefrontal cortex, left anterior temporal lobe, and right insular cortex. Future studies of these potential biomarkers in ADHD patients with comorbidities are warranted.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Multiple, but not single, exposures to general anesthesia in children before age of 3 increased the risk of ADHD.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Biochem Biophys Res Commun. 2021 Nov 19:S0006-291X(21)01515-1. doi: 10.1016/j.bbrc.2021.11.012. Online ahead of print.NO ABSTRACTPMID:34809988 | DOI:10.1016/j.bbrc.2021.11.012
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Source Type: research
Am Psychol. 2021 Nov 22. doi: 10.1037/amp0000816. Online ahead of print.ABSTRACTReports on remote psychotherapies for youth (e.g., technology-based treatment) suggest it is acceptable, feasible, and useful in overcoming logistical barriers to treatment. But how effective is remote care? To find out, PsycINFO and PubMed were searched from 1960 through 2020, supplemented by journal searches and reference trails, to identify randomized controlled trials of youth psychotherapy for anxiety (including obsessive-compulsive disorder and trauma), depression, attention-deficit/hyperactivity disorder (ADHD), or conduct problems, in w...
Source: The American Psychologist - Category: Psychiatry & Psychology Authors: Source Type: research
AbstractThis Taiwan study examined the associations of parental age and mental disorders with the offspring risks of attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), major depressive disorder (MDD), and bipolar disorder (BD). Children born between January 1991 and December 2004 in Taiwan were enrolled as the birth cohort (n = 4,138,151) and followed up until December 2011. A logistic regression analysis was performed to identify the odds ratio (OR). The advanced age effects were significant in ADHD (range of OR: 1.04 to 1.49) and ASD (range of OR: 1.35 to 2.27). Teenage mothers...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
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