Characterizing the Effect of Processing Technique and Solution Type on Cytomorphology Using Liquid-Based Cytology

Conclusions: The most significant difference affecting the cytoplasmic and nuclear areas was the processing technique. The TP method increased the cytoplasmic and nuclear areas, while the methanol-based PreservCyt solution enabled the highest enlargement of the cell. LBC is a superior preparation technique for standardization of the specimens. Our results offer a better understanding of methods suitable for specimen preparation for developing precision AI-based diagnosis in cytology.Acta Cytologica
Source: Acta Cytologica - Category: Cytology Source Type: research