De-escalation of axillary irradiation for early breast cancer – has the time come?

Decades of progress in early breast cancer (BC) treatment, in particular advances in early detection and tumor-biology-driven systemic therapy have resulted in improvements in both local/distant control and overall survival (OS) [1]. Resultant improved disease control together with the morbidity associated with locoregional treatments have led to locoregional treatment (surgery and radiation) de-escalation attempts, aiming to decrease treatment-related sequelae and – as a result – improve patients’ quality-of-life.

Source: Cancer Treatment Reviews - October 7, 2021 Category: Cancer & Oncology Authors: El żbieta Senkus, Maria Joao Cardoso, Orit Kaidar-Person, Aleksandra Łacko, Icro Meattini, Philip Poortmans Source Type: research