Determination of effective concentrations of drug absorption enhancers using in vitro and ex vivo models

CONCLUSION: Incorporation of the drug absorption enhancers (e.g., curcumin and quercetin), at specific concentrations, in dosage forms could improve the bioavailability of the BCS Class III and IV drugs that are substrates of CYP3A4 and p-glycoprotein.PMID:34601070 | DOI:10.1016/j.ejps.2021.106028

Source: European Journal of Pharmaceutical Sciences - October 3, 2021 Category: Drugs & Pharmacology Authors: Poloko Stephen Kheoane Gillian Mary-Anne Enslin Clemence Tarirai Source Type: research