Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection

Gastrointestinal (GI) symptoms including vomiting, abdominal discomfort and diarrhoea have been reported in coronavirus infections at the onset of hospitalisation, affecting 10-30% of patients (Parasa et al., 2020). SARS-CoV-2 RNA has been detected in faeces and stomach, duodenum and colon biopsies (Lin et al., 2020; Zhao et al., 2020). COVID-19 patients with ongoing diarrhoea have displayed enhanced concentration of faecal calprotectin (a marker of gut inflammation), as well as systemic interleukin (IL)-6 production, regardless of the viral load (Effenberger et al., 2020).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: SHORT COMMUNICATION Source Type: research