Cervical cancer: what's new in classification, morphology, molecular findings and prognosis of glandular precursor and invasive lesions

The recently published 5th edition of the WHO Classification of Female Genital Tumours has incorporated the new International Endocervical Adenocarcinoma Criteria and Classification (IECC) system for endocervical adenocarcinomas, based on morphological features linked to aetiology (Human Papillomavirus -HPV infection) as well as the Silva pattern-based classification. It is considered as a reliable system to predict patients at risk of lymph node metastases, recurrences and death from disease. Both classification systems, help to individualize clinical management and are presented in detail in this review along with most recently identified prognostic parameters and molecular findings.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: Update on pathology of female genital tract tumours Source Type: research