GSE176139 RNAseq of rabbit lungs infected with Mycobacterium tuberculosis as single cells or aggregates

Contributor : Selvakumar SubbianSeries Type : Expression profiling by high throughput sequencingOrganism : Oryctolagus cuniculusThe virulence of Mycobacterium tuberculosis (Mtb), either as mostly aggregates or single cells (Mtb-SC), was compared using a rabbit model of pulmonary infection. Our hypothesis is that aggregation contributes to enhanced virulence of Mtb. Rabbit lung transcriptome was analyzed by RNAseq to identify differentially regulated gene networks and pathways between Mtb-AG and Mtb-SC infection of rabbit lungs soon after seeding of the bacteria (24 hours post-inoculation).

Source: GEO: Gene Expression Omnibus - September 22, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Oryctolagus cuniculus Source Type: research