Transcriptomic Changes During Stage Progression of Mycosis Fungoides

CONCLUSION: Stage progression in MF is associated with Th2/Th9 polarization of malignant cells, activation of proliferation, survival, as well as increased genomic instability. Global transcriptomic changes in multiple lesions may be caused by hematogenous cell percolation between discrete skin lesions.PMID:34528236 | DOI:10.1111/bjd.20760

Source: The British Journal of Dermatology - September 16, 2021 Category: Dermatology Authors: M Z X Xiao D Hennessey A Iyer S O'Keefe F Zhang A Sivanand R Gniadecki Source Type: research