The impact of CD4+CD28null T lymphocytes on atrial fibrillation: a potential pathophysiological pathway

ConclusionConsidering the available data in the literature, it needs to be assumed that CD4+CD28null T lymphocytes are mainly involved in the development of AF and disease progression. Of utmost importance, it can be considered as the result of a T-cell-mediated auto-immune reaction among myocardial tissue. However, mechanisms which recruit CD4+CD28null cells in cardiac tissue remain unclear and need further investigation.
Source: Inflammation Research - Category: Research Source Type: research