Autoimmune & inflammatory nmd

Sporadic inclusion body myositis (sIBM) is a slowly progressive inflammatory myopathy developing in the elderly. Though there is distinct evidence of coexisting inflammatory and degenerative mechanisms in sIBM, its true pathogenesis remains unknown. On electromyography (EMG), both myogenic and neurogenic changes are often detected in sIBM; however, again, the mechanism remains unknown. Therefore, this study addressed this question pathologically. We extracted sIBM cases based upon the European Neuromuscular Centre criteria (2011) among patients who underwent a muscle biopsy from 2008 to 2020.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research