Renal agenesis, associated genital malformations, and responsible genes
The study of the possible genetic causes of complex genital malformations is a subject of great interest both to know its etiology and diagnosis and for the best genetic and reproductive advice in these patients. Recently, Chen et al. (1) published the article titled “Perturbations of Genes Essential for Müllerian Duct and Wolffian Duct Development in Mayer-Rokitansky-Kuster-Hauser Syndrome,” and in this issue of Fertility and Sterility, Li et al. (2) reported that “whole-exome sequencing revealed that renal agenesi s-related genes were mutated and may be associated with the Herlyn-Werner-Wunderlich syndrome.” This is interesting and deserves some comments on the issue of renal agenesis (unilateral renal agenesis [URA] vs.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Pedro Aci én, Maribel Acién Tags: Reflections Source Type: research