Time and residual hematopoiesis are crucial for PNH clones escape in hepatitis-associated aplastic anemia

In conclusion, PNH clones were infrequent in newly diagnosed HAAA, but their frequency increased to one that was similar to the IAA frequency during follow-up. These results suggest that the PNH clone selection/expansion process is dynamic and takes time to establish, confirming that retesting for PNH clones during follow-up is crucial.
Source: Annals of Hematology - Category: Hematology Source Type: research