Three Novel Structural Variations at MHC and IL12B Predisposing to Psoriasis

CONCLUSIONS: Our study constructed the most comprehensive SV map for psoriasis thus far and enriched the genetic architecture and pathogenesis of psoriasis as well as highlighted the nonnegligible impact of SVs on complex diseases.PMID:34498260 | DOI:10.1111/bjd.20752

Source: The British Journal of Dermatology - September 9, 2021 Category: Dermatology Authors: Q Zhen Y Zhang Y Yu H Yang T Zhang X Li X Mo B Li J Wu Y Liang H Ge Q Xu W Chen W Qian H Xu G Chen B Bai J Zhang Y Lu S Chen H Zhang Y Zhang X Chen X Li X Jin X Lin L Yong M Fang J Zhao Y Lu S Wu D Jiang J Shi H Cao Y Qiu S Li X Kang J Shen H Ma S Sun Y F Source Type: research