Africa: J & J Reports Promising Ebola Vaccine Data

[Tunis Afrique Presse] Washington/United States -- Johnson&Johnson said on Monday its Ebola vaccine regimen demonstrated antibody immune responses in adults and children, citing data published in the Lancet Infectious Diseases journal.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Bjorkman The H1N1 pandemic of 2009-2010, MERS epidemic of 2012, Ebola epidemics of 2013-2016 and 2018-2020, Zika epidemic of 2015-2016, and COVID-19 pandemic of 2019-2021, are recent examples in the long history of epidemics that demonstrate the enormous global impact of viral infection. The rapid development of safe and effective vaccines and therapeutics has proven vital to reducing morbidity and mortality from newly emerging viruses. Structural biology methods can be used to determine how antibodies elicited during infection or vaccination target viral proteins and identify viral epitopes that correlate with potent...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Condition:   Ebola Intervention:   Biological: ChAdOx1 biEBOV Sponsor:   University of Oxford Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Am Fam Physician. 2021 Oct 1;104(4):376-385.ABSTRACTBioterrorism is the deliberate release of viruses, bacteria, toxins, or fungi with the goal of causing panic, mass casualties, or severe economic disruption. From 1981 to 2018, there were 37 bioterrorist attacks worldwide. The Centers for Disease Control and Prevention (CDC) lists anthrax, botulism, plague, smallpox, tularemia, and viral hemorrhagic fevers as category A agents that are the greatest risk to national security. An emerging infectious disease (e.g., novel respiratory virus) may also be used as a biological agent. Clinicians may be the first to recognize a bio...
Source: American Family Physician - Category: Primary Care Authors: Source Type: research
[WHO-AFRO] Brazzaville/Kinshasa -- Ebola vaccination began today in the Democratic Republic of the Congo's North Kivu Province where a case was confirmed on 8 October. People at high risk, including contacts of the confirmed case and first responders will receive the doses as the health authorities move to curb the spread of the virus.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
NEW BRUNSWICK, N.J. (October 12, 2021) – Johnson &Johnson (NYSE: JNJ) today announced that Paul Stoffels M.D., currently Vice Chairman of the Executive Committee and Chief Scientific Officer of Johnson &Johnson, will retire from the Company effective December 31, 2021.As the Vice Chairman of the Executive Committee and Chief Scientific Officer, Dr. Stoffels spearheaded the company’s research and product pipeline leading teams across sectors to set the company-wide mandate to discover and develop transformational healthcare solutions. Under his leadership, Johnson &Johnson revitalized its innovation ...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Our Company Source Type: news
On Oct. 6, the World Health Organization recommended use of the first vaccine to fight malaria. The decision is momentous and highly anticipated for many reasons: among them is that this is the first vaccine to help reduce the risk of deadly severe malaria in young children in Sub-Saharan Africa, where the disease remains a leading killer. The vaccine offers hope that there can be a circle of learning from one pandemic to the next. Malaria, our oldest pandemic, may offer insights on how we can survive contemporary scourges like COVID-19. Malaria evolved at least 2.5 million years ago and first infected humans in rural part...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized health healthscienceclimate Source Type: news
BEERSE, BELGIUM, October 6, 2021 – The Janssen Pharmaceutical Companies of Johnson &Johnson (Janssen) announced today, in collaboration with the KU Leuven Rega Institute and the KU Leuven Centre for Drug Design and Discovery (CD3), the publication of new preclinical data in the journal Nature showing that an early-stage compound with a novel mechanism of action could potentially treat all serotypes of dengue fever and provide a period of protection against acquiring the dengue virus. Janssen is now moving its dengue program into clinical development. Data from the early-stage study suggest that an antiviral compo...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Comp Med. 2021 Oct 5. doi: 10.30802/AALAS-CM-21-000062. Online ahead of print.ABSTRACTThe significant advances made by the global scientific community during the COVID-19 pandemic, exemplified by thedevelopment of multiple SARS-CoV-2 vaccines in less than 1 y, were made possible in part because of animal research.Historically, animals have been used to study the characterization, treatment, and prevention of most of the major infectious disease outbreaks that humans have faced. From the advent of modern 'germ theory' prior to the 1918 Spanish Flu pandemic through the more recent Ebola and Zika virus outbreaks, research tha...
Source: Comparative Medicine - Category: Zoology Authors: Source Type: research
Annu Rev Med. 2021 Oct 5. doi: 10.1146/annurev-med-012621-102252. Online ahead of print.ABSTRACTThe worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the unprecedented pace of development of multiple vaccines. This review evaluates how adenovirus (Ad) vector platforms have been leveraged in response to this pandemic. Ad vectors have been used in the past for vaccines against other viruses, most notably HIV and Ebola, but they never have been produced, distributed, or administered to humans at such a large scale. Several different sero...
Source: Annual Review of Medicine - Category: General Medicine Authors: Source Type: research
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