Dexmedetomidine protects the heart against ischemia reperfusion injury via regulation of the bradykinin receptors

CONCLUSIONS: DEX regulates BK receptor expression and potentiates the protection of BK in cardiac I/R injury, which suggests that modulating endogenous cardioprotective factors may play an important role in DEX-induced cardioprotection.PMID:34506777 | DOI:10.1016/j.ejphar.2021.174493

Source: European Journal of Pharmacology - September 10, 2021 Category: Drugs & Pharmacology Authors: Jinchao Song Jiankui Du Xing Tan Zhaotang Wu Jihong Yuan Binhai Cong Source Type: research