Targeting ARID1A Mutations in Cancer

Potential Therapeutic Targets for ARID1A AlterationsCaption: Multiple potential therapeutic targets exist for cancers with ARID1A alterations. There is evidence that ARID1A alterations lead to resistance to platinum-based chemotherapy, and mixed evidence regarding the efficacy of PARP inhibitors.

Source: Cancer Treatment Reviews - September 5, 2021 Category: Cancer & Oncology Authors: Jaren Mullen, Shumei Kato, Jason K. Sicklick, Razelle Kurzrock Source Type: research