Factors associated with new persistent opioid use after ankle sprain: a cross-sectional analysis

Background: Chronic opioid use is a growing crisis in the United States. The authors examined the risk factors associated with new persistent opioid use in patients who had nonoperatively treated ankle sprains and offer evidence-based treatment recommendations for practitioners. Methods: A United States insurance claims database was used to select patients who underwent nonoperative treatment of an ankle sprain between January 2008 and December 2016. The authors examined opioid prescribing 1 yr before diagnosis and 6 mo after and defined new persistent opioid use as prescription fulfillment between 91 and 180 days after injury. We evaluated the effect of patient factors and amount prescribed on the likelihood of new persistent opioid use and the probability of refill within 30 days using logistical regression analysis. Results: A total opioid dose of 150 mg oral morphine equivalents (OMEs) prescribed within 7 days of diagnosis was the greatest modifiable risk factor for new persistent opioid use [adjusted odds ratio (aOR) 1.38, 95% confidence interval (CI), 1.28 to 1.49, P
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Special Focus: Practice Perspectives Source Type: research