The CREBRF diabetes-protective rs373863828-A allele is associated with enhanced early insulin release in men of M āori and Pacific ancestry

Conclusions/interpretationrs373863828-A allele associates with increased glucose-stimulated insulin release without affecting insulin sensitivity, suggesting thatCREBRF p.Arg457Gln may increase insulin release to reduce the risk of type 2 diabetes.Graphical abstract
Source: Diabetologia - Category: Endocrinology Source Type: research