Examination of the molecular mechanism of the mutual inhibitory effect of each cytotoxicity caused by the combined extraction of Coptidis Rhizoma and Rhei Rhizoma: An example of providing evidence for ‘herbal pair’ theory

ConclusionFrom these results, when CR and RR are extracted together, their cytotoxicity is suppressed by some unknown mechanism. Whether this is due to the synthesis of new compounds by co-extraction or the detoxification of toxic components by interaction needs further investigation. This result suggests the importance of ‘herbal pair’ research.
Source: Traditional and Kampo Medicine - Category: Complementary Medicine Authors: Tags: ORIGINAL ARTICLE Source Type: research