O-041 Functional sperm diagnostics: The evidence behind commercially available tests

Abstract textDespite the fact that the semen analysis has remained the cornerstone of the male infertility evaluation for decades, it has significant limitations. Among them are the inability to completely predict reproductive potential and the inability to analyze the fitness of individual sperm. There remains a real need for novel tests that can determine which interventions for male infertility are the most likely to result in a significant improvement in reproductive potential, to analyze the chance of success or failure with ART and to determine if there exists a sub population of sperm whose use could lead to optimal chances of success with fertility treatments. In this talk we will cover what the limitations of the current semen analysis are, what novel tests are available and delve into the impact of future technologies such as microfluidics, machine learning and others to optimize the diagnostic armamentarium of male fertility assessment. We will also focus on tools that could, potentially, non-invasively image sperm and report reproductive fitness while maintaining viability for ART.Trial registration number:Study funding:Funding source:
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research