Overview of the First NRG Oncology-National Cancer Institute Workshop on Dosimetry of Systemic Radiopharmaceutical Therapy

This article will also contrast currently available methods and tools with those used in the past, to propose a pathway whereby dosimetry helps the field by optimizing the biologic effect of the treatment and trial design in the drug approval process to reduce financial and logistical costs. We also briefly discuss the dosimetric equivalent of biomarkers to help bring a precision medicine approach to RPT implementation when merited by evidence collected during early-phase trial investigations. Advances in the methodology and related tools have made dosimetry the optimum biomarker for RPT.

Source: Journal of Nuclear Medicine - July 30, 2021 Category: Nuclear Medicine Authors: Roncali, E., Capala, J., Benedict, S. H., Akabani, G., Bednarz, B., Bhadrasain, V., Bolch, W. E., Buchsbaum, J. C., Coleman, N. C., Dewaraja, Y. K., Frey, E., Ghaly, M., Grudzinski, J., Hobbs, R. F., Howell, R. W., Humm, J. L., Kunos, C. A., Larson, S., L Tags: Special Contributions Source Type: research