Shenzhi Jiannao formula ameliorates vascular dementia in vivo and in vitro by inhibition glutamate neurotoxicity via promoting clathrin-mediated endocytosis

Synaptic damage and glutamate excitotoxicity have been implicated in the pathogenesis of vascular dementia (VD). Clathrin, RAB5B and N-methyl-d-aspartic acid receptor 1 (NMDAR1) proteins play a vital role in endo...

Source: Chinese Medicine - July 28, 2021 Category: Complementary Medicine Authors: Danfeng Tian, Yangyang Guo, Dandan Zhang, Qiang Gao, Ganlu Liu, Jingfeng Lin, Ze Chang, Yuchun Wang, Rui Su and Zhenyun Han Tags: Research Source Type: research