Circulating extracellular vesicles from individuals at high-risk of lung cancer induce pro-tumorigenic conversion of stromal cells through transfer of miR-126 and miR-320

CONCLUSION: Overall our data provide a new perspective on the pro-tumorigenic role of circulating EVs in high risk smokers and highlight the significance of miR-320-EVs as a new prognostic biomarker in lung cancer patients.PMID:34289890 | DOI:10.1186/s13046-021-02040-3

Source: Clinical Lung Cancer - July 22, 2021 Category: Cancer & Oncology Authors: Francesca Pontis Luca Roz Mavis Mensah Miriam Segale Massimo Moro Giulia Bertolini Ilaria Petraroia Giovanni Centonze Anna Maria Ferretti Paola Suatoni Ugo Pastorino Orazio Fortunato Gabriella Sozzi Source Type: research