Microcrystal electron diffraction supports a new drug development pipeline

(CCDC - Cambridge Crystallographic Data Centre) Solving structures of potential therapeutics using X-ray diffraction (XRD) is usually a pivotal step in drug development. But XRD generally requires large, well-ordered crystals. Advancements in automated data collection and processing have increased interest in electron diffraction as an XRD alternative. Electron diffraction uses a beam of electrons rather than X-rays to obtain structures. Here researchers present a new drug development pipeline using electron diffraction for use when XRD may not be an option.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news