Utility of fractional exhaled nitric oxide in interstitial lung disease
The majority of interstitial lung diseases (ILDs) develop rapidly and are associated with a poor
prognosis. Therefore, new noninvasive markers are needed to guide the classification and
prognostication of ILD. We enrolled 95 patients with ILD, including dermatomyositis-associated ILD (
n = 69), Sj ögren’s syndrome-associated ILD ( n = 7), mixed connective tissue disease-associated ILD
( n = 9), idiopathic pulmonary fibrosis ( n = 5) and hypersensitivity pneumonitis ( n = 5), 82
patients with connective tissue disease but without ILD as well as 24 healthy controls, then
evaluated fractional exhaled nitric oxide (FeNO50; 50 ml s –1 ) (Bisenkov et al 2006 Vestn. Khir.
Im. I. I. Grek. 165 9 –14), pulmonary function and high-resolution computed tomography (HRCT) scores.
Blood samples were analyzed and bronchoalveolar lavage fluid parameters were measured. There was no
significant difference in FeNO50 values between different s...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Yu Zheng, Yueyan Lou, Feng Zhu, Xiaodong Wang, Wanlong Wu and Xueling Wu Source Type: research
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