Amenorrhea and Estrogen Disorders in Kidney Disease

Summary: Sexual and reproductive function are impacted negatively in individuals with chronic kidney disease and end-stage renal disease.  Disruption of the hypothalamic–pituitary–gonadal axis plays a pivotal role in contributing to these manifestations as a result of decreasing kidney function and the development of uremia. Early menopause is encountered commonly in women with reduced kidney function, and treatment is problemati c as a result of reduced kidney function changing the half-life of medications.
Source: Seminars in Nephrology - Category: Urology & Nephrology Authors: Source Type: research