Multiple Intravitreal Liposomal Amphotericin B for a Case of < b > < i > Candida glabrata < /i > < /b > Endophthalmitis

We report a case ofCandida glabrata endophthalmitis which was effectively treated by intravitreal liposomal amphotericin B (L-AMB) injection. A 72-year-old man was referred to our department for positive blood culture ofCandida glabrata. First ophthalmologic examination revealed a chorioretinal lesion in left eye, and the patient was diagnosed as possible candida chorioretinitis. Despite systemic antifungal therapy, his chorioretinal lesion increased in both eyes and complicated by vitritis. Intravitreal administration of L-AMB was introduced for probable candida endophthalmitis. Finally, improvement of vitritis and regression of chorioretinal lesions were obtained by total of 9 times intravitreal injection. Our case suggests the safety and efficacy of intravitreal L-AMB injection forCandida glabrata endophthalmitis.Case Rep Ophthalmol 2021;12:485 –491

Source: Case Reports in Ophthalmology - June 11, 2021 Category: Opthalmology Source Type: research