Congenital lung disease: multiple entities you may not have encountered

Congenital lung disease comes to the attention of the surgical pathologist through lung biopsy or excision of a lung lobe. The two most frequent clinical indications are removal of a mass, often detected antenatally, or investigation of difficulty in ventilation or oxygenation. The diagnostic possibilities in each instance are different. The mass is most commonly a cystic airway malformation, but a limited number of rare neoplasms enters the differential diagnosis. Biopsy in the case of difficulty in ventilation most often shows delayed alveolar development, but surfactant protein disorder and a small number of lethal developmental abnormalities must be excluded.

Source: Diagnostic Histopathology - June 3, 2021 Category: Pathology Authors: Michael T. Ashworth, J. Ciaran Hutchinson, Mohammad Haini Tags: Mini-symposium: Cardiothoracic pathology Source Type: research