Differential associations of APOE- ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia

ConclusionOur data suggest that the established protective effect of theAPOE- ε2 allele against developing clinical AD is primarily linked to resistance against A β deposition rather than tau pathology.
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research