COVID-19 Vaccines and the Skin: The landscape of cutaneous vaccine reactions worldwide

In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is increasingly important for dermatologists to recognize potential cutaneous adverse events. In this article we review the dermatologic manifestations of COVID-19 vaccines worldwide as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection reactions were the most common cutaneous side effects observed in clinical trials, while delayed injection reactions were the most common cutaneous side effect reported outside of clinical trials. Understanding the landscape of cutaneous manifestations to COVID-19 vaccines is key to providing appropriate vaccine guidance.
Source: Dermatologic Clinics - Category: Dermatology Authors: Source Type: research